If receive the following error on the IIS server and either have to restart IIS or reboot the server: dir=ltr " ">
It is not possible to run different versions of ASP.NET in the same IIS process. Please use the IIS Administration Tool to reconfigure your server to run the application in a separate process.
Please refer to the Microsoft article http://www.microsoft.com/technet/prodtechnol/WindowsServer2003/Library/IIS/d2cc4557-dbe7-46f9-9b63-df1d09f17c6a.mspx?mfr=true
Scroll down to the section Application Pooling in IIS 6.0 and read the information on why this erro rmay occur and how to assign the application (in this case AyaNovaWBI) to its own Application Pool so that it runs only using .NET 2 or higher.